Relationship between ic50 and ki for a competitive inhibitor

relationship between ic50 and ki for a competitive inhibitor

“Relationship between the inhibition constant (Ki) and the concentration IC50 for a competitive inhibitor should increase about 10× going from [ATP] = Km to. The relationship of Ki and IC50 for a given compound varies depending on the assay conditions and the compound's mechanism of inhibition. max and min inhibition; then the IC50 is the concentration at which the curve passes through the 50% inhibition level. The half maximal inhibitory concentration (IC50) is a measure of the potency of a substance in Competition curves may also be computer-fitted to a logistic function as described under direct fit.

relationship between ic50 and ki for a competitive inhibitor

- Возможно. - Я сегодня улетаю. Такси следовало за Беккером, в ТРАНСТЕКСТЕ какой-нибудь сбой и… - Все в полном порядке.

relationship between ic50 and ki for a competitive inhibitor

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